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View All Genomic Data PBM Motif Data PBM Clones Minimize All

-Genomic Data for NKX2-5				Links
Protein NKX2-5	UniPROBE Accession Number UP00604	Species Homo sapiens	Domain Homeobox	Swiss-Prot P52952
Name and Synonyms Name: homeobox protein Nkx-2.5. Synonyms:Cardiac-specific homeobox, CHNG5, CSX, CSX1, FLJ52202, FLJ97166, FLJ97195, FLJ97197, FLJ99536, Homeobox protein CSX, Homeobox protein NK-2 homolog E, Homeobox protein Nkx-2.5, NKX2.5, NKX2E, NKX4-1				IHOP 87507
Description This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.				NCBI RefSeq NP_001159647
NKX2-5 DNA binding domain 1   RKPRVLFSQA QVYELERRFK QQRYLSAPER DQLASVLKLT STQVKIWFQN 51  RRYKCKR				JASPAR None Available

-PBM Motif Data for NKX2-5_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble) Reverse Complement (RC)				PWM Save
				Top Kmer AAGTACTT E.S. 0.499 AAGTACTT E.S. 0.499
Downloads Download the zip of all NKX2-5_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.

-PBM Motif Data for NKX2-5_K183E_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble) Reverse Complement (RC)				PWM Save
				Top Kmer CCACTTGA E.S. 0.498 TCAAGTGG E.S. 0.498
Downloads Download the zip of all NKX2-5_K183E PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.

-PBM Motif Data for NKX2-5_R161P_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble) Reverse Complement (RC)				PWM Save
				Top Kmer AAGTACTT E.S. 0.498 AAGTACTT E.S. 0.498
Downloads Download the zip of all NKX2-5_R161P PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.

-PBM Motif Data for NKX2-5_R190C_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble) Reverse Complement (RC)				PWM Save
				Top Kmer TATA..TATA E.S. 0.481 TATA..TATA E.S. 0.481
Downloads Download the zip of all NKX2-5_R190C PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.

-PBM Motif Data for NKX2-5_T178M_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble) Reverse Complement (RC)				PWM Save
				Top Kmer AT.TA.ATTA E.S. 0.479 TAAT.TA.AT E.S. 0.479
Downloads Download the zip of all NKX2-5_T178M PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.

Download Data for NKX2-5 (all alleles)
Downloads Download the zip of all NKX2-5 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.

-NKX2-5 Datasets
Clone	Clone Type	Last Modified	Save	View
NKX2-5_REF	DNA binding domain only
NKX2-5_REF Insert Sequence 1   TEADNAERPR ARRRRKPRVL FSQAQVYELE RRFKQQRYLS APERDQLASV 51  LKLTSTQVKI WFQNRRYKCK RQRQDQTLEL VGLPPP
NKX2-5_K183E	DNA binding domain only
NKX2-5_K183E Insert Sequence 1   TEADNAERPR ARRRRKPRVL FSQAQVYELE RRFKQQRYLS APERDQLASV 51  LKLTSTQVEI WFQNRRYKCK RQRQDQTLEL VGLPPP
NKX2-5_R161P	DNA binding domain only
NKX2-5_R161P Insert Sequence 1   TEADNAERPR ARRRRKPRVL FSQAQVYELE RRFKQQPYLS APERDQLASV 51  LKLTSTQVKI WFQNRRYKCK RQRQDQTLEL VGLPPP
NKX2-5_R190C	DNA binding domain only
NKX2-5_R190C Insert Sequence 1   TEADNAERPR ARRRRKPRVL FSQAQVYELE RRFKQQRYLS APERDQLASV 51  LKLTSTQVKI WFQNRCYKCK RQRQDQTLEL VGLPPP
NKX2-5_T178M	DNA binding domain only
NKX2-5_T178M Insert Sequence 1   TEADNAERPR ARRRRKPRVL FSQAQVYELE RRFKQQRYLS APERDQLASV 51  LKLMSTQVKI WFQNRRYKCK RQRQDQTLEL VGLPPP
References Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016